S052 Atopic Dermatitis
DESCRIPTION
Open admission to eligible categories, no tuition or ticket
This session provides an up-to-date overview about atopic dermatitis, new discoveries and new therapies. the session is directed towards dermatologists and other health providers who treat adults and/or children with atopic dermatitis. Moderated by Dr Paller, topics to be reviewed are: Epidemiology and Comorbidities of Atopic Dermatitis (Dr Drucker); Epidermal Barrier and its Role (Dr Samuelov); Immune System and Relevance to Targeted Therapeutics (Dr Guttman-Yassky); Microbiome and Atopic Dermatitis (Dr Hata); Topical Therapy (Dr Eichenfield); Systemic therapy for Adults (Eric Simpson, MD, MCR); Systemics for Pediatric Patients (Dr Paller)
LEARNING OBJECTIVES
Recognize the high burden and comorbidities of atopic dermatitis
Identify barrier and immune shifts in atopic dermatitis that for the basis for new therapies
Use improved understanding available of emergent therapies in making decisions on atopic dermatitis management
SCHEDULE
8:00 PM
Introduction to the session
Amy S. Paller, MD, FAAD
8:05 PM
Epidemiology and Comorbidities of Atopic Dermatitis
Aaron Mark Drucker, MD, FAAD
8:30 PM
The Epidermal Barrier and its Role
8:55 PM
Immune System Shifts in Atopic Dermatitis
Emma Guttman, MD, PhD, FAAD
9:20 PM
How the Microbiome Impacts Atopic Dermatitis
Tissa R. Hata, MD, FAAD
9:40 PM
New and Emerging Topical Therapy
Lawrence F Eichenfield, MD, FAAD
10:05 PM
Systemic Therapy for Adults
Eric Lawrence Simpson, MD, FAAD
10:30 PM
Systemics for Pediatric Patients
Amy S. Paller, MD, FAAD
10:50 PM
Last Chance for Questions
SPEAKERS
Aaron Mark Drucker, MD, FAAD
Lawrence F Eichenfield, MD, FAAD
Emma Guttman, MD, PhD, FAAD
Tissa R. Hata, MD, FAAD
Alan D. Irvine, MD
Amy S. Paller, MD, FAAD
Eric Lawrence Simpson, MD, FAAD
HANDOUTS
SPEAKER DISCLOSURES
Aaron Mark Drucker, MD, FAAD
No financial relationships exist with ineligible companies.
Lawrence F Eichenfield, MD, FAAD
AbbVie – Consultant(Honoraria); Abbvie – Investigator(Grants/Research Funding); Almirall – Consultant(Honoraria); Amgen – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding); Amryt Pharma – Consultant(Honoraria); Arcutis Biotherapeutics – Investigator(Grants/Research Funding); ASLAN Pharmaceuticals – Advisory Board(Honoraria), Consultant (1099 relationship)(Honoraria); Bristol-Myers Squibb – Consultant(Honoraria); Castle Biosciences, Inc – Investigator(Grants/Research Funding); Dermata Therapeutics – Consultant (1099 relationship)(Stock); Dermavant Sciences, Inc. – Consultant(Honoraria); Eli Lilly – Consultant(Honoraria), Investigator(Grants/Research Funding); Elsevier Inc. – Other(Patent royalties or other compensation for Intellectual Property Rights); Forte Biosciences – Board of Directors(Fees), Board of Directors(Stock Options); Galderma Laboratories, L.P. – Consultant(Honoraria), Investigator(Fees); Incyte Corporation – Consultant(Honoraria); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Honoraria); Krystal Biotech, Inc – Consultant(Honoraria); LEO Pharma, US – Consultant(Honoraria), Investigator(Fees); Lilly ICOS LLC – Consultant(Honoraria); Nobelpharma – Consultant(Honoraria); Ortho Dermatologics – Investigator(Grants/Research Funding); Pfizer Inc. – Consultant(Honoraria), Investigator(Grants/Research Funding); Sanofi/Regeneron – Consultant(Honoraria), Investigator(Fees); TopMD – Consultant(Stock Options); TrialSpark, Inc. – Consultant(Honoraria); UCB – Consultant(Honoraria); Verrica Pharmaceuticals Inc – Board of Directors(Fees), Board of Directors(Stock Options); Wiley-Blackwell – Other(Honoraria);
Emma Guttman, MD, PhD, FAAD
AbbVie – Consultant(Fees), Consultant(Honoraria); Almirall – Consultant(Fees), Consultant(Honoraria); Amgen – Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding); AnaptysBio – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Apogee Therapeutics – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Apollo Therapeutics Ltd – Investigator(Grants/Research Funding); Artax Biopharma – Consultant (1099 relationship)(Fees), Consultant (1099 relationship)(Honoraria); ASLAN – Investigator(Grants/Research Funding); AstraZeneca – Consultant (1099 relationship)(Fees), Consultant (1099 relationship)(Honoraria); Boehringer Ingelheim – Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding); Bristol-Myers Squibb – Advisory Board(Fees), Advisory Board(Honoraria), Consultant(Fees), Consultant(Honoraria); Cara Therapeutics – Advisory Board(Honoraria), Investigator(Grants/Research Funding); Centrexion Therapeutics Corporation – Consultant (1099 relationship)(Fees); Concert Pharmaceuticals – Investigator(Grants/Research Funding); Connect Biopharma LLC – Consultant(Fees), Consultant(Honoraria); Eli Lilly and Company – Advisory Board(Honoraria), Consultant(Honoraria), Consultant (1099 relationship)(Fees); Enveda Biosciences – Consultant (1099 relationship)(Fees); Escient Pharmaceuticals, Inc – Consultant (1099 relationship)(Fees); Fairmount Funds Management LLC – Consultant (1099 relationship)(Fees); Forest Laboratories – Consultant (1099 relationship)(Fees); Galderma Research & Development, LLC – Advisory Board(Honoraria), Consultant(Honoraria), Consultant (1099 relationship)(Fees); Gate Bioscience – Consultant(Honoraria), Consultant (1099 relationship)(Fees); GlaxoSmithKline – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); GlaxoSmithKline Immunology – Consultant (1099 relationship)(Fees); Google Ventures – Consultant (1099 relationship)(Fees); Horizon Therapeutics USA, Inc – Consultant (1099 relationship)(Fees); Incyte Corporation – Advisory Board(Honoraria), Consultant(Honoraria), Consultant (1099 relationship)(Fees); janssen – Consultant(Honoraria); Janssen Biotech – Consultant (1099 relationship)(Fees); Janssen Pharmaceuticals, Inc – Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Japan Tobacco Inc. – Consultant (1099 relationship)(Fees); Jasper Therapeutics – Consultant (1099 relationship)(Fees); JT Central Pharmaceutical Research Institute – Consultant (1099 relationship)(Fees); Kyowa Hakko Kirin Pharma, Inc. – Advisory Board(Honoraria), Consultant(Honoraria), Consultant (1099 relationship)(Fees), Investigator(Grants/Research Funding); Leo Pharma Inc – Advisory Board(Honoraria), Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding); Merck – Consultant(Fees), Consultant(Honoraria); Nektar Therapeutics – Consultant (1099 relationship)(Fees); Novartis Pharmaceuticals Corporation – Consultant (1099 relationship)(Fees); NUMAB Therapeutics AG – Consultant (1099 relationship)(Fees); OrbiMed Advisors LLC – Consultant (1099 relationship)(Fees); Otsuka Pharmaceutical Co., Ltd. – Consultant (1099 relationship)(Fees); Pfizer Inc. – Advisory Board(Honoraria), Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding); Pharmaxis Ltd – Consultant (1099 relationship)(Fees); Pioneering Medicine VII, Inc – Consultant (1099 relationship)(Fees); Pioneering Medicines – Consultant (1099 relationship)(Fees); Proteologix US Inc – Consultant (1099 relationship)(Fees); RAPT Therapeutics – Consultant (1099 relationship)(Fees), Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding), Stockholder(Stock Options); Regeneron – Advisory Board(Honoraria), Consultant(Fees), Consultant(Honoraria); Regeneron Pharmaceuticals, Inc. – Investigator(Grants/Research Funding); RibonTherapeutics, Inc., – Consultant (1099 relationship)(Fees); Sanofi – Advisory Board(Honoraria), Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding); SATO Pharmaceutical Co., Ltd – Consultant(Fees), Consultant(Honoraria); Schro¨dinger, Inc – Consultant (1099 relationship)(Fees); Sun Pharma Advanced Research Company (SPARC) – Consultant (1099 relationship)(Fees); Teva – Consultant (1099 relationship)(Fees); Teva Pharmaceutical Industries Ltd. – Consultant (1099 relationship)(Fees); UCB – Consultant(Fees), Consultant(Honoraria), Investigator(Grants/Research Funding);
Tissa R. Hata, MD, FAAD
Bristol-Myers Squibb – Investigator(Grants/Research Funding); Eli Lilly and Company – Investigator(Grants/Research Funding); Janssen Pharmaceuticals, Inc – Investigator(Grants/Research Funding); Pfizer Inc. – Investigator(Grants/Research Funding); Unilever – Investigator(Grants/Research Funding);
Alan D. Irvine, MD
AbbVie – Consultant(Honoraria); Arena Pharmaceuticals – Consultant(Honoraria); Eli Lilly and Company – Consultant(Fees); Janssen Pharmaceuticals, Inc – Advisory Board(Honoraria); Regeneron – Advisory Board(Honoraria); Regeneron Pharmaceuticals, Inc. – Investigator(Honoraria); Sanofi Genzyme – Advisory Board(Honoraria);
Amy S. Paller, MD, FAAD
AbbVie – Consultant(Honoraria), Investigator(Grants/Research Funding); Apogee BioPharm – Consultant (1099 relationship)(Honoraria); Applied Pharma Research – Investigator(Grants/Research Funding); Arcutis Biotherapeutics – Consultant (1099 relationship)(Honoraria); ASLAN Pharmaceuticals – Consultant (1099 relationship)(Honoraria); BioCryst Pharmaceuticals, Inc. – Consultant (1099 relationship)(Honoraria); Biomendics LLC – Investigator(Grants/Research Funding); Boehringer Ingelheim – Consultant(Honoraria); Bristol-Myers Squibb – Consultant(Honoraria); Dermavant Sciences, Inc. – Investigator(Grants/Research Funding); Galderma Laboratories, L.P. – Consultant(Honoraria); Incyte Corporation – Investigator(Grants/Research Funding); Krystal Biotech, Inc – Consultant(Honoraria), Investigator(Grants/Research Funding); L'Oréal France – Consultant (1099 relationship)(Honoraria); Leo Pharma Inc – Consultant(Honoraria); Mitsubishi Tanabe Pharma Corporation – Consultant (1099 relationship)(Honoraria); MoonLake Immunotherapeutics – Consultant (1099 relationship)(Honoraria); Procter and Gamble – Consultant (1099 relationship)(Honoraria); Regeneron – Consultant(Honoraria), Investigator(Grants/Research Funding); Sanofi Genzyme – Consultant(Honoraria); Timber Pharmaceuticals – Investigator(Grants/Research Funding); UCB – Consultant (1099 relationship)(Honoraria), Investigator(Grants/Research Funding);
Eric Lawrence Simpson, MD, FAAD
AbbVie – Consultant(Fees), Investigator(Grants/Research Funding); Acrotech Biopharma Inc – Investigator(Grants/Research Funding); Amgen – Consultant(Fees), Investigator(Grants/Research Funding); Arcutis Biotherapeutics – Consultant(Fees); Arcutis, Inc. – Investigator(Grants/Research Funding); Areteia Therapeutics – Consultant (1099 relationship)(Fees); ASLAN – Consultant(Fees); ASLAN Pharmaceuticals – Investigator(Grants/Research Funding); Bristol-Myers Squibb – Consultant(Fees); Castle Biosciences – Investigator(Grants/Research Funding); CorEvitas – Consultant(Fees), Investigator(Grants/Research Funding); Corvus Pharmaceuticals – Consultant (1099 relationship)(Fees); Demira – Consultant(Fees); Dermavant Sciences, Inc. – Investigator(Grants/Research Funding); Dermira – Investigator(Grants/Research Funding); Eli Lilly and Company – Consultant(Fees), Investigator(Grants/Research Funding); Evelo Biosciences, Inc. – Consultant(Fees); FIDE – Speaker/Faculty Education(Fees); Forte Biosciences – Consultant(Fees); Galderma Laboratories, LP – Consultant (1099 relationship)(Fees); Gilead Sciences, Inc – Consultant (1099 relationship)(Fees); GlaxoSmithKline – Consultant(Fees); Impetus Healthcare – Consultant (1099 relationship)(Fees); Incyte Corporation – Consultant(Fees), Investigator(Grants/Research Funding); Innovaderm Research Inc. – Consultant (1099 relationship)(Fees); Janssen Research & Development, LLC – Consultant(Fees); Johnson & Johnson Pharmaceutical Research & Development – Consultant(Fees); Kymab – Investigator(Grants/Research Funding); Kyowa Hakko Kirin Pharma, Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Leo Pharma Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Med Learning Group – Consultant(Fees); Merck – Advisory Board(Fees); National Jewish Health – Investigator(Grants/Research Funding); Novartis – Investigator(Grants/Research Funding); NUMAB Therapeutics AG – Consultant (1099 relationship)(Fees); Pfizer Inc. – Consultant(Fees), Investigator(Grants/Research Funding); Physicians World LLC – Consultant(Fees); Prime Education – Speaker/Faculty Education(Honoraria); Recludix Pharma – Consultant (1099 relationship)(Fees); Regeneron – Consultant(Fees), Investigator(Grants/Research Funding); Roivant Sciences – Consultant(Fees); Sanofi – Investigator(Grants/Research Funding); Sanofi Genzyme – Consultant(Fees), Investigator(Grants/Research Funding); SITRYX – Consultant (1099 relationship)(Fees); Target RWE – Investigator(Grants/Research Funding); Tioga Pharmaceuticals, Inc. – Investigator(Grants/Research Funding); Trevi Therapeutics – Consultant(Fees); Valeant Pharmaceuticals International – Consultant(Fees); Vanda Pharmaceuticals Inc. – Investigator(Grants/Research Funding); Veriskin – Investigator(Grants/Research Funding); Vindico Medical Education – Speaker/Faculty Education(Honoraria); WebMD – Consultant(Fees);