C014 Structure and Function of the Skin: Development, Cell Biology, and Skin Structure
DESCRIPTION
Tuition fee and ticket required for admission
This session will present a state-of-the-art understanding of skin science for practicing clinicians and high-yield knowledge for candidates preparing for the boards. We will teach the development and functions of the skin with an emphasis on cell components and structures involved in pathophysiology of skin diseases. Topics include skin embryology, differentiation and patterning; functions of keratinocytes and melanocytes; cell-cell adhesion structures; and intracellular signaling pathways and epigenetic modifications. Emphasis will be placed on clinical examples and how knowledge of skin structure and function can improve understanding of skin disease pathogenesis and managing therapeutics. This activity has been approved by the American Board of Dermatology (ABD) for up to 30 Continuous Certification Program (CCP) Component 2 Self-Assessment points. For more information about CCP, please visit the ABD website at www.abderm.org
LEARNING OBJECTIVES
Describe the embryonic origin, patterning, and structure of cells that comprise the skin and the intracellular structures that connect these cells together.
Describe the functions of epidermal keratinocytes and melanocytes and their relevance in skin diseases.
Name and describe the key genetic and epigenetic pathways that regulate skin homeostasis and how they are altered in skin diseases.
SCHEDULE
8:00 PM
Introduction to the Session
Bryan Sun, MD, PhD
8:05 PM
How does skin develop?
Bryan Sun, MD, PhD
8:40 PM
Keratinocytes: Structure and functions
Carolyn S. Lee, MD, PhD, FAAD
9:15 PM
Melanocytes: Regulating pigmentation and the path to neoplasm
Jennifer Y Lin, MD, FAAD
9:50 PM
Holding it Together: Cell adhesion and immunobullous diseases
M. Peter Marinkovich, MD, FAAD
10:25 PM
Genetic and epigenetic mechanisms in the skin
Brian Capell, MD, PhD
SPEAKERS
Brian Capell, MD, PhD
Carolyn S. Lee, MD, PhD, FAAD
Jennifer Y Lin, MD, FAAD
M. Peter Marinkovich, MD, FAAD
Bryan Sun, MD, PhD
HANDOUTS
SPEAKER DISCLOSURES
Brian Capell, MD, PhD
No financial relationships exist with ineligible companies.
Carolyn S. Lee, MD, PhD, FAAD
No financial relationships exist with ineligible companies.
Jennifer Y Lin, MD, FAAD
No financial relationships exist with ineligible companies.
M. Peter Marinkovich, MD, FAAD
No financial relationships exist with ineligible companies.
Bryan Sun, MD, PhD
Anthem Blue Cross/Blue Shield subsidiary of Wellpoint – Consultant(Honoraria);